A short intro to Dihexa
Alzheimer’s disease is a disorder characterized by poor memory and generally diminished cognitive functions. It is estimated that over 5 million Americans and more than 44 million across the world live with Alzheimer’s disease! The condition mostly affects the elderly, and it’s actually very fatal with 1 in every 3 seniors dying of either Alzheimer’s or another form of dementia. To put it in perspective, Alzheimer’s kills more people than both breast and prostate cancer combined! The fatality rate aside, the impact of Alzheimer’s on the patient’s quality of life is simply jaw-dropping.
Numerous clinical studies have been funded in search for an effective treatment for the condition. Over the years, so many medications have been produced. However, a majority of the drugs have been focusing on stopping or slowing down the progression of the disease. Very few pharmaceuticals have managed to come up with drugs that can actually reverse the effects of Alzheimer’s.
Dihexa is one of the few drugs that try to reverse the effects of the disease on the patients. This doesn’t just serve to stop the progression of the condition, but it can actually restore and enhance the quality of life. It, therefore, makes perfect sense that the drug is a favorite among many people in the medical community.
In restoring the impact of Alzheimer’s disease, Dihexa repairs the damage suffered in the synapse of neurons. In simpler terms, it enhances the patient’s memory and cognition. That sounds a lot like a nootropic, doesn’t it? Well, yes, it does, and that’s why Dihexa’s potential in treating Alzheimer’s disease has had an unprecedented effect on making it popular in the nootropic industry.
What is Dihexa?
Dihexa is an oligopeptide medication that is derived from angiotensin IV. Scientists from Washington State University produced it for the treatment of neurodegenerative conditions like Alzheimer’s. The drug is also known by the code name PNB-0408 or N-hexanoic-Tyr-lle-(6) aminohexanoic amide. Dihexa has a high affinity to HGF (hepatocyte growth factor). It binds to HGF and potentiates its activities at the c-Met receptor.
What makes Dihexa so popular is not just the ability to reverse the effects of Alzheimer’s, but it’s also how powerful the drug is. So powerful that it has been nicknamed the “Neurogenic Wonder Drug.” In fact, researchers believe that Dihexa can be 10 million times stronger than the Brain-Derived Neurotrophic Factor (BDNF), which is considered to be the gold standard of neuronal connections.
How Does Dihexa Work?
Dihexa works by increasing synaptogenesis. It is an orally-active first-in-class compound that passes through the blood-brain barrier and enhances both memory consolidation and retrieval.
Since the drug helps to form new functional synapses, it facilitates augmentation of synaptic connectivity through the newly formed synapses to treat not just memory issues but motor dysfunctions as well.
The proven ability of Dihexa to treat memory and motor dysfunctions means that its benefits are not just limited to Alzheimer’s disease. Actually, one of the researchers behind the drug, Joe Harding, explains that Dihexa can also be very helpful in treating other conditions such as brain traumas and neurodegenerative diseases where neuronal connections are damaged or lost.
Does this mean Dihexa can be used as a Nootropic? Well, Dihexa is formulated to treat Alzheimer’s disease, and so the research on other non-neurodegenerative applications is very limited. Even though the effects of the drugs seem to be very beneficial to almost everyone, there is no sufficient clinical trial to show that healthy people can benefit from it. Moreover, there is no evidence to show that daily usage of the drug (which is how nootropics are typically used) is safe in healthy people.
So, in as much as Dihexa can be very useful for your memory and overall cognitive performance, using it as a nootropic supplement may not be a good idea due to the lack of scientific evidence in this area.
What Are the Benefits of Dihexa?
Some of the health benefits of Dihexa include:
- Improves focus
- Enhances learning
- Increases mental stamina
- Improves both short and long term memory
- Enhances creative thinking and conversational skills
- Boosts social intuition
- Improves heart health
- Improves hair health
- Improves symptoms of depression
- Some people reported improved problem-solving skills.
Some of these benefits have been proven by research studies, while others are based on anecdotal evidence alone.
It’s ethical to point out that some people have been using Dihexa as a nootropic but did not report any significant changes to their cognition. This shouldn’t be surprising, especially if the users are not suffering from any neurodegenerative disease.
Side Effects of Dihexa
Just like other drugs, Dihexa comes with a fair share of its own side effects. The incidence rate, based on anecdotal evidence, is relatively low, though. The most interesting thing is that continued use of Dihexa can result in withdrawal symptoms when the user tries to stop taking the drug. Most of the people who went through this reported mild effects such as jitters, headaches, and irritability. There haven’t been any severe effects reported so far.
It’s important to remember that Dihexa is a fairly new compound in the market with minimal trials. The possible long-term effects of the drug remain unknown. It’s also best that you consult your medical provider before using this drug, especially if you are already taking other medications. Pregnant and nursing women should also avoid the drug unless a licensed physician approves it.
The recommended Dihexa dosage is 8 to 45 mg. It’s advisable that anyone using the drug as a nootropic supplement to consult their doctor first and start with the lowest dosage. The drug should be used orally with a dropper.
Take note that a lot of the stores selling Dihexa will not take liability for any side effects or complications related to the use of their “smart drug.” Therefore, if you decide to use the drug for this purpose, remain vigilant on the doses you are taking and avoid mixing it with other drugs unless you have the approval of a physician.