IDRA-21 Review : Benefits, Side Effects and Where To Buy


If there was a pill on the market that promised to make anyone smarter without causing any unwanted side effects, so many people, if not everyone, would line up for it. Everyone wants that extra cutting edge to perform better.

Nootropics are a set of drugs or supplements that are formulated with that in mind. These supplements contain ingredients that are believed to enhance different aspects of the brain. However, nootropics are dietary supplements, which means that the FDA does not regulate them. For that reason, all nootropics don’t perform the same way, and their formulas are not scrutinized properly. Also, there is usually limited clinical data on these drugs. For these reasons, some nootropics do not work at all, while others can cause an array of adverse reactions.

IDRA-21 is one of the many nootropics on the market today. But is it one of the few such drugs that actually work? Is IDRA-21 safe? Let’s find out:


What is IDRA-21?

IDRA-21, according to scientists, is a positive allosteric modulator of AMPA receptors that are derived from benzothiadiazole. The drug belongs in the class of drugs known as Ampakines that are known to interact with the glutamate AMPA receptors. Ampakines have grown to become quite popular in the nootropics industry. These drugs are said to produce results similar to stimulants but without the uncomfortable side effects.

Just like with other nootropics, finding human trials on IDRA-21 is a challenge. However, several animal studies have shown that Ampakines and IDRA-21 in specific, can help with improving memory, focus, and other cognitive functions.

The compound has also been compared to another common drug, aniracetam, that is used in reversing cognitive deficits. According to the data from researchers, IRA-21 is between 10 to 30 times more potent than aniracetam for this purpose. Moreover, IDRA-21 was seen to have a more sustainable effect. It’s reported that IDRA-21 remained effective in the system for up to 48 hours after ingestion. This means that the compound can comfortably be used once in 2-3 days, and the users will still get the best from it. That’s definitely better than nootropics that must be used every day, with some demanding several servings in a day for them to remain active in your system.


Benefits of IDRA-21

IDRA-21 is an ampakine drug with nootropic properties. It is believed to enhance cognitive performance in different ways:

  1. Improves Mental Focus

Attention deficit is a serious problem at the moment. A lot of people can get away with this, but if you are in a profession where details matter or if you are a student, having laser-sharp focus and improved attention for an extended period is a resource that might just give you the extra boost you need to outdo the competition.

IDRA-21 is a nootropic that improves mental focus and increases attention span. It helps to shield you from the distractions within or around you, thus allowing you to give the task at hand your full focus. This has been reported in animal studies. There is also anecdotal evidence to support the same.

  1. Improves Short Term Memory

Short-term memory problems are more prevalent in the elderly population. However, even some younger people can experience the same problems. And, it doesn’t just affect your professional life, but it can also go as far as hurting your personal life, especially if you are surrounded by people who don’t understand the condition.

The use of IDRA-21 has been linked to improved short-term memory. It helps to improve your everyday life. There have been reports that it can even be effective in the treatment of amnesia.

  1. Boosts Motivation

Motivation is important not just in getting you started with your tasks but also in making sure that you are producing results of the highest standards. Think about it; without motivation, you can do something, but the results will be nowhere as desirable as they would be if you carried out the task with lots of motivation. With motivation, you also get to enjoy what you are doing, so it feels natural and effortless.

This is another area where you will find IDRA-21 very helpful.  The compound will boost your motivation, thus increasing your efficiency as well as productivity.

  1. Improves Symptoms of Neurodegenerative Disorders

Alzheimer’s and Parkinson’s disease are some of the most common neurodegenerative disorders. They affect millions of people across the world, with thousands of them dying every year. Since IDRA-21 improves synaptic transmission by causing allosteric activation, the drug can also be very helpful in reversing some of the effects of neurodegenerative disorders.

Sadly, with the lack of sufficient human trials, it’s hard to tell how impactful it can be for this purpose. We also don’t know how exactly it can be used to treat the conditions.

IDRA-21 is also believed to be very helpful for the treatment of anxiety and depression. It can also boost longevity.

What Are the Side Effects of IDRA-21?

Proper use of IDRA-21 has not been associated with any side effects. People who have adhered to the recommended dosage have always enjoyed the vast benefits of IDRA-21 without any complications. However, abusing the drug increases the risk of adverse reactions such as:

  • Anxiety
  • Dizziness
  • Sweating
  • Headaches
  • Nausea
  • Vomiting
  • Insomnia
  • Restlessness
  • Mood swings

The other group that is likely to experience the above side effects are people whose AMPA activity or glutamate neurotransmission is already at optimal levels. Taking IDRA-21 in such instances will cause adverse reactions.

It’s best to speak to your doctor before taking IDRA-21 if you have a preexisting medical condition. Individuals who have suffered a stroke before are strongly advised against taking this drug.

IDRA-21 Dosage

Due to the lack of human trials on IDRA-21, it’s very hard to conclusively tell one dose that is guaranteed to work for everyone. But, since the nootropic is very popular, so many people have shared their experiences with different doses. Based on this, we can say that the ideal dose of IDRA-21 is around 10mg.

Given the long half-life of the drug, it’s vital that you only use it once in 48 hours.

First-time users should not start with a 10mg dose. That’s too high, and it increases the risk of adverse reactions significantly. It’s wiser to start with a much lower dose to give your system some room to adapt to the new compound. You can proceed to increase the dose gradually while keeping a close eye to the reactions you are getting. Most people don’t even get to the 10mg dosage as they find sweet spots with 8mg or less. So, take your time to monitor your reactions and settle for a dose that is giving you the results you need without any adverse reactions.

Where Can I Buy IDRA-21

IDRA-21 is available on multiple online stores that specialize in research chemicals. This is because IDRA-21 is also sold as a research chemical and not a dietary supplement. In simpler terms, stores can not recommend human consumption of IDRA-21 due to the limited human research on the compound, which makes it hard to tell the possible dangers of its consumption.

That said, it is available in powder and capsule form. Prices also range depending on the store and the quantity you are ordering. Half a gram of the drug can cost about $14, while a full gram can go for roughly $21.

Final Thoughts

IDRA-21 has so much potential. It can improve memory, focus, cognition, and motivation. It’s also believed to be very helpful for the treatment of Alzheimer’s and Parkinson’s disease. What’s even more enticing is the fact that with proper use, you will never experience any side effects and that it remains active within your system for 48 hours.

But then we cannot forget that it is just a research chemical with limited human trials. It is also not regulated by the FDA. For that reason, you have to be very careful about where you are buying the compound and how you are using it. Don’t take more than 10mg within 48 hours. It’s also best to consult your medical provider before using it.

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