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Nolvadex: A Closer Look at This SERM Medication

Frank Merano · March 17, 2019 ·

Table of Contents

  • Introduction to Nolvadex
    • Cancer Treatment
    • Steroid Use
    • Side Effects of Nolvadex
    • Dosage
    • In Cancer Patients
    • As Part of an Anabolic Cycle
    • Conclusions
      • Related Posts

Introduction to Nolvadex

Nolvadex is the modern brand name for Tamoxifen Citrate. The medicine was created in 1961 by a company called ICI. The change in brand name came about when ICI changed its name to AstraZeneca, one of the world’s largest pharmaceutical brands.

In recent years there has been mounting competition in the form of generic products. The medicine also faces competition from new cancer drugs from Novartis and Pfizer, as well as new products from AstraZeneca itself.

The medicine does, however, still have a range of intriguing benefits.

Nolvadex plays an important role in breast cancer treatment, but it has also become immensely popular among people who undergo a cycle of anabolic steroids.

Cancer Treatment

The medicine is used primarily as a method of treating breast cancer which has spread around a patient’s body and it can also be used to treat breast cancer following surgery or radiation therapy. Finally, medicine is also used to help high-risk patients mitigate their risk of developing breast cancer.

The medicine achieves this because it is a selective estrogen receptor modulator (SERM). This means that the medicine is, essentially, capable of interfering with the effects of estrogen within the body. it is the most popular SERM on the market.

This means that the medicine is particularly effective against those cancers which are hormone responsive and essentially use estrogen as fuel for growth. By binding to estrogen receptors, it blocks estrogen from performing its action on certain parts of the body.

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Steroid Use

The drug has also become immensely popular among people looking to build muscle while improving their overall body strength through the use of anabolic steroids. This is because Nolvadex is both an estrogen antagonist and agonist, meaning that it makes estrogen behave differently in different parts of the body.

This means that medicine can help people on a steroid cycle to prevent the onset of side effects related to estrogens, such as the development of male breast tissue and water retention. This is why it is used as part of Post Cycle Therapy to help restore testosterone to normal levels.

Side Effects of Nolvadex

As with any potent medicine, Nolvadex has the potential to lead to a range of side effects. Studies and empirical data have demonstrated that women are more susceptible to the side effects when compared to men and that Nolvadex has a lower level of risk when compared to most other SERMs.

The most common side effects experienced by recipients include:

  • Hot flashes
  • An upset stomach
  • Headaches
  • Itching, bleeding, or discharge from the vagina

There are a variety of more severe symptoms too, but these are experienced far less frequently:

  • Endometrial changes
  • Pulmonary embolism
  • Increased triglyceride levels
  • Reduced white blood cell count
  • Rashes on the skin

As mentioned, these particular side effects are very rare. It is also important that female patients speak with their consultant regarding pregnancy, given that use of the drug has the potential to cause damage to the child in uteri.

Discussions with consultants and health professionals will also help the patient to determine how susceptible they may be to particular side effects. If the medicine is being taken by those women who have breast cancer which has spread to other parts of the body, they may experience increased pain but this is often considered to be a sign of a good response to the medication.

Dosage

The recommended dosage varies from patient to patient and according to the use case. The medicine is offered in both liquid and tablet forms.

The requirements for the possession of the medicine vary from country to country, with many requiring a prescription. The medicine can, however, be purchased easily and freely online for low prices. This black market is where the majority of steroid users will purchase their product.

In Cancer Patients

The dosage will vary from person to person according to the existing medical condition and the responses which are seen to therapy. With that said, the average dose which will be administered will generally lie between 10 and 20 mg to be taken twice a day and the initial administration may have a higher concentration.

Once a patient has successfully overcome their cancer, it will generally be recommended that they continue to take the medicine in the average dosage each day for the remainder of their lives.

As Part of an Anabolic Cycle

Users of anabolic steroids also have a standard dose of 10 to 20 mg each day. This quantity is sufficient to help subvert estrogenic side effects and mitigate the risk of developing male breast tissue. If, however, it is not sufficient then an aromatase inhibitor may be used.

The dosage will change when the steroid user moves into their Post Cycle Therapy. Here, the average dose will begin at 40 mg each day for several weeks. The dosage will then be halved to 20 mg for an additional period of time before being reduced to 10 mg each day until the cycle is completed.

The appropriate quantity will vary from person to person and the specific Post Cycle Therapy that they are pursuing. Ascertaining the appropriate quantity is a challenge for users of steroids and mistakes can lead to reduced efficacy.

Conclusions

This medicine offers truly remarkable results in patients suffering from breast cancer. Its relatively cheap price, combined with its ease of consumption and low risk of side effects, makes it one of the leading SERMs on the market. it’s very commonly used and it is one of the primary tools in the fight against breast cancer.

For many anabolic steroid users, it’s absolutely the SERM of choice. Given that it is cheap, easy to obtain and incredibly effective it has become a favorite among those users. This is why most Post Cycle Therapy plans will include Nolvadex in order to retain lean muscle mass, help restore natural testosterone production and avoid estrogenic side effects.

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