Pramiracetam Review: Pro’s & Con’s and Best Place To Buy


There is a category of people who do not appear to work hard to perform well at work or academically. Undoubtedly, some individuals have better cognitive capacities, can grasp new information faster, and have a sharper memory.

Meanwhile, others have to strive extra hard to realize the same level of understanding, and even experience difficulties focusing on one task at a time.

However, new research on brain enhancement supplements indicates that one can improve their fluid intelligence with smart drugs.

In this case, Pramiracetam is one among this cutting-edge class of supplements, touted to boost learning and memory without the risk of side effects.

Remember the drug in Limitless? Could this drug be the modern-day, real-life pill used in the film? Anyway, while it’s not like this Pramiracetam will make a genius out of anyone, it would be quite something if it can provide results that are even remotely close.

The following guide will break down everything there is to know regarding this new supplement, and eventually, we will understand the limits of what it can accomplish.


What is Pramiracetam?

Pramiracetam is a racetam-class supplement and a synthetic relative of Piracetam. It belongs to a broader group of drugs known as nootropics and has been the subject of ongoing research ever since it was first discovered and patented by researcher Parke-Davis.

This supplement is flaunted to be among the most potent nootropics to grace the scene and is said to increase mental performance and various intelligence metrics. Among the racetam drugs, Piracetam was the first one to be developed, but numerous advancements have taken place to establish the latest member of the family. In fact, Pramiracetam is believed to be 30 times more potent than its original predecessor.

In addition to enhancing memory formation ad sensory perception, this nootropic also acts as a neuroprotective agent and can prevent memory loss and stall overall cognitive decline.

In addition to working well solo, this supplement plays very well with other nootropics, helping to propel their effect to new levels. Consequently, its flexibility has made it a staple among students, writers, people in technical jobs, and anyone looking to boost their cognitive abilities.

Since it was patented, this supplement has been subjected to rigorous research for treating memory issues associated with brain injuries and diseases such as Alzheimer’s. Regardless, this drug is yet to be cleared by the FDA for any specific use.

That said, this nootropic enhancement has attained considerable success in Europe under the brand names Pramistar, Neupramir and Remen, and is usually prescribed for the treating conditions such as ADHD, dyslexia, and dementia.

What Are the Benefits of Pramiracetam?

Foremost, this supplement is a proper nootropic, developed specifically to enhance cognition. Its benefits include the following.

  • Improving Memory

As a proven memory enhancer, this supplement has been extensively tested over the decades and has proven effective for both animal studies and clinical trials of youth with cognitive damage due to brain injuries.

Pramiracetam enhances memory by triggering the hippocampus, a part of the brain primarily responsible for forging new memories, and by functioning as a potent anti-amnesic that lessens forgetfulness.

The dual action makes this supplement highly effective at boosting memory, and many users have reported substantial improvement in recall, a claim that has been substantiated by numerous studies.

  • Enhanced Alertness and Learning Capacity

This particular benefit has made this nootropic a staple among students seeking a reliable study aid.

Despite the absence of human studies on these particular effects, animal research reveals that this supplement contributes to the mechanisms responsible for learning and improvement of memory by elevating levels of nitric oxide synthase (NOS) activity in the hippocampus.

The activity of NOS is associated with brain plasticity and neural development, both of which are crucial to all aspects of cognition.

Moreover, this nootropic is said to increase the uptake of high-affinity choline in the hippocampus, thereby circuitously facilitating the production of acetylcholine, a crucial neurotransmitter that is strongly associated with cognition and learning.

  • Enhances Cognitive Function

As a proper nootropic and one of the best at that, Pramiracetam has far-reaching impacts on cognition. There is sufficient scientific and anecdotal evidence to corroborate the effectiveness of this supplement in this context.

For instance, this nootropic was found to normalize the activity of brain waves. This means that senior citizens who are facing the onset of cognitive decline can benefit tremendously from this supplement.

  • Promote Social Fluency

This perk is solely reliant on anecdotal evidence. However, numerous users have reported that taking this supplement makes them creative in their conversations. This aspect may be attributable, at least partially to this nootropic’s well-known emotional blunting effect. This impact may reduce social anxiety, eventually enhancing social fluency.

  • Protects the Brain Neurons

This nootropic is renowned for its considerable neuroprotective impacts, capable of enhancing cognition in individuals who have experienced brain trauma. Research findings also indicate that it has discernable neuroprotective effects when used during coronary bypass surgery, as well as in the treatment of cognitive disorders of cerebrovascular origin.

A few other perks of using this supplement include a better flow of blood to the brain, higher oxygen uptake, and improved glucose metabolism. All these changes add up to higher mental energy, a feeling of mental alertness, clarity of thought, and better visual and auditory sensory perception.

  • Stacking Pramiracetam

It is crucial to note that this nootropic can function as a potent enhancement on its own. However, when taken with other nootropics, it can be a powerful potentiator, boosting their effects to various degrees.

This is predominantly true when it is stacked together with other racetams, making it an obvious inclusion in many nootropic stacks.

Stacking with Noopept, a peptide can also be an excellent option. However, given that the increase in effect may be unpredictable, one is recommended to use Pramiracetam on its own to establish their level of tolerance. Subsequently, they can proceed slowly.

Stacking this nootropic with energy-enhancing supplements like adranafil or oxiracetam usually intensifies mental sharpness and makes it last longer.

What’s more, stacking this supplement with aniracetam can alleviate feelings of mental strain and anxiety, provide you with increased focus, concentration, and an improved mood.

Stacking Pramiracetam with cholines is also quite the in thing, and is done to enhance the effects of the nootropic, adding cholines can also reduce headaches, one of the most frequently documented side effects of taking Pramiracetam.

Pramiracetam Dosage

While there is no standard dosage for taking this nootropic, a daily intake of 1000 mg to 1500 mg should be sufficient to give you the results you seek.

You will want to split the daily dosage into two or three servings due to the short half-life of Pramiracetam (5 hours).

It is crucial to note that there is quite some flexibility regarding the optimal dosage, and different amounts will work for different people. Moreover, various people will react differently to the compound, and you will realize that your tolerance builds up over time.

The best approach is to start with a lower dose of about 800 mg per day and increase your uptake slowly according to your tolerance.

Taking this nootropic in pill form is most convenient. However, if you settle for the powder form, you must factor in that Pramiracetam is fat-soluble. Consequently, mixing it with water won’t do any good.

Usually, one is advised to use it with some lipid such as fish oil, milk, olive oil, or to consume it with a meal containing healthy fat sources.

Is Pramiracetam Safe?

One of the best things about this supplement is that it is well-tolerated even at extremely high doses. The nootropic is considered to be low risk, and very few side effects have been documented.

Headaches are the most common side effects and are usually an indication that your brain is running low on choline. Supplementation with choline eradicates this one immediately.

Feelings of agitation and nervousness have also been reported in several cases. This is usually caused by taking doses that are too high for one’s tolerance, and typically go away the moment the dose is reduced reasonably.

This nootropic has no known side effects for using it over extended periods. In fact, the reverse is true. Study findings indicate that using this nootropic for the long term, may promote healthy brain function and even repair age-related cognitive damage.

Where to Purchase Pramiracetam

Well, the best place to find this supplement effortlessly is in online outlets. Regardless of the seller you choose, ensure that the product is tested and approved by a third party laboratory body.


So, what do you think? First, we have to concede that this nootropic is nothing compared to the drug depicted in Limitless. However, you will also agree that Pramiracetam is by far one of the best smart drugs, if not the best in the industry at the moment.

You will rarely come across such a powerful supplement without side effects. What’s more, you can use this nootropic for an extended period without any concerns.

Overall, this nootropic is globally accepted as a safe and effective nootropic supplement. If you are interested in boosting your learning speed, memory, and overall mental acuity, this supplement is worth considering.

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