Cardarine (GW501516) Review: Where to Buy, Effects and Benefits.


WHAT IS CARDARINE ANYWAY?

Cardarine has a lot of names and numerical markings. Some might know the compound as Endurbol or cardarine gw-501516. No matter the name, the research chemical is the same.

Cardarine actually has quite a history. The compound was first developed in the 1990s by ligand pharmaceuticals as a part of a cancer treatment trial. As a chemical developed for this specific purpose, it has a lot of benefits, as one would imagine. However, no drug is without side effects, but we’ll discuss that a bit later.

A SARM OR SOMETHING ELSE?

The interesting thing about Cardarine is that it isn’t actually a SARM. Both SARMs and GW501516 are becoming increasingly popular in the bodybuilding community. However, they aren’t from the same family of performance enhancers.

SARMs are selective androgen receptor modulators. That basically means that SARMs influence the receptors that receive signals from androgen receptors. Is GW501516 the same?

While many think the answer is yes, they are wrong. Cardarine gw-501516 is actually a peroxisome proliferator activator receptor delta that increases fat loss. That means that it doesn’t modulate the work of the androgen receptors in bones and muscles to increase muscle mass as SARMs do.

Cardarine can have positive effects on the digestive system, which can lead to fat building and skeletal muscle gain, among other things. This also explains why it’s commonly confused with SARMs. This PPAR delta activator (peroxisome proliferator) also has positive effects on the vascular and the nervous systems, and liver and kidney function.

THE HISTORY OF CARDARINE

As mentioned, Cardarine was developed as part of cancer treatment research. The primary goal was to create a chemical that can stop tumor growth. Namely, GW501516 was supposed to target colon, breast, and prostate tumors and prevent their formation.

Yet, during the trial, the research team found interesting results.GW501516 also had positive effects on lipid, as well as vascular health. Among the surprising results were also:

  • higher levels of endurance
  • increased fat loss and it prevents obesity
  • and lowering the severeness of type 2 diabetes symptoms in rats.
  • increased levels of HDL cholesterol
  • increases wound healing

Thus, it is only logical to assume what train of thought led athletes, especially bodybuilders, to turn to Cardarine gw-501516. It burns body fat and increases muscle gain. In fact, it offers all the benefits of anabolic steroids, albeit on a much smaller scale, without testicle shrinking and liver failure. What’s more, GW501516 can have a beneficial effect on a damaged liver. It really sounds like a bodybuilder’s dream come true, right? But is it?

 

MEDICAL USES AND BENEFITS OF GW501516

After the initial research, back in the 90s, scientists discovered that GW501516 has plenty of potential uses in medicine. Fat loss, higher endurance, and muscle tissue gain are the most important benefits for bodybuilders. But Cardarine also affects the vascular system, liver, and kidney function.

  • The vascular system

One of the major effects of Cardarine is that the compound lowers cholesterol levels and therefore decreases the risk of heart rate attacks. However, it also directly affects blood vessels and arteries. Because it has anti-inflammatory properties, Cardarine diminishes the effects of oxidative damage and it also boosts the nitric oxide levels in your arteries.

Researchers found that GW501516 significantly reduced the risk of heart disease. What’s more, potential complications of cardiovascular diseases were also affected.

Cardarine prevents plaque buildup in the arteries and protects them from damage. Furthermore, the compound can also accelerate the growth of new cells and blood vessels.

Yet, this benefit is the proverbial double-edged sword. It can also stimulate the growth of other cells that aren’t beneficial at all — cancer cells.

  • The nervous system

The fact that Cardarine has positive effects on blood flow vessels is also beneficial. It means that it can diminish the risk of strokes and hemorrhage in the brain. Furthermore, some trials hint that this chemical can also have positive effects on the development of brain cells.

Other research shows that anti-inflammatory properties may actually cause brain cell damage.

  • The effects on liver cells

The liver is the principal target of Cardarine. As we know, it has a crucial role in storing, releasing, and burning fats. That’s why the effects that Cardarine has are especially beneficial for bodybuilders. Compared to other fat burners, Cardarine will burn fat fast.

Our blood sugar levels go down when the liver switches from glucose as an energy source to fatty acids. That’s precisely what Cardarine causes the liver to do. Furthermore, it can also prevent insulin resistance, non-alcoholic damage, cell death and resistance to liver inflammation.

THE BENEFITS OF CARDARINE FOR ATHLETES

Of course, as bodybuilders, we are mostly interested in four features of GW501516:

  • Fat burning and prevents obesity
  • Muscle tissue growth
  • Increases stamina and metabolism
  • Prevention of Kidney disease
  • Decreases health risks
  • Better heart health
  • Faster wound healing

When it comes to fat burning, the good news is that GW501516 was researched as a part of clinical studies on human subjects. Science shows that this chemical activates the genes in charge of burning fat. What’s more, it also increases energy use. Thus, it actively boosts your system so that it burns belly fat as an energy source.

This is also very beneficial to obese people. Cardarine diminishes the symptoms of metabolic disorders, as it increases fat burning levels. What’s more, it decreases liver fat, insulin levels, and blood fats by 10 to 30% according to some animal studies.

How Cardarine enhances fat burning

Cardarine works by blocking the formation of fatty acid chains as it activates muscle fibers. Essentially, this means that it prevents the body from storing fat, as well as using it as an energy source. The results are similar to the “starvation mode” that the body goes into when food intake is scarce. Yet with Cardarine, there is no muscle mass deterioration or muscle “cannibalization.”

Furthermore, enhanced stamina, as a side effect of GW501516, leads to an increase in physical activity. People who use it have more strength and endurance. Thus, building muscle mass and developing a more muscular, lean figure is easier.

Tissue recovery

Not to mention Cardarine also improves tissue recovery. A healthier liver function allows for a faster recovery time. Of course, this is amazing news for bodybuilders. Cardarine can reduce “rest” time. That means that we can keep a more rigorous training program. It works both for bulking and for cutting.

While on that subject, it’s important to note that Cardarine is a very versatile chemical. It can be used in any program, and we can stack it with virtually any other chemical and other SARMs.

POTENTIAL SIDE EFFECTS

We all know the horror stories that come with the territory of anabolic steroids. Liver damage, vascular damage, destroyed reproductive organs — we all try to stay away from that. So what happens when we hear about a magic pill that promises fantastic results? Naturally, we want to know — what’s the catch?

However, it seems as though there isn’t a catch. Healthy individuals who use Cardarine and stick to proper dosages shouldn’t experience any side effects. That’s not to say there aren’t any.

Extensive animal studies done on rats and mice have shown that GW501516 could potentially cause liver damage. Still, the research was done on mice with pre-existing liver disease. Furthermore, individuals with certain issues, as well as pregnant women should avoid using it.

RECOMMENDED DOSAGE AND USES OF CARDARINE

When it comes to Cardarine dosage, the sweet spot is somewhere between 10 and 20mg per day. What’s more, the intake should be once a day. For beginner bodybuilders and amateurs just looking to lose fat, a lower dose might be enough. However, athletes and bodybuilders should take around 20mg before a workout.

The important thing to remember is that the compound has a half-life of 16 to 24 hours. Therefore, you’ll often hear bodybuilders taking their recommended dosage in two parts — twice daily.

Furthermore, the recommended cycle is around 12 weeks. This is a bit longer than most SARM cycles. Still, since Cardarine isn’t actually a SARM, that’s understandable. Furthermore, Cardarine doesn’t need any PCT (post-cycle therapy).

Due to the lack of significant side effects, prolonged use isn’t as frowned upon. Still, keep in mind that any abuse can potentially lead to particular consequences.

A FEW PARTING WORDS

Overall, for those of us looking for a safe, clean performance enhancer —GW501516 is an excellent choice. The benefits-to-side-effects ratio is almost too good to be true. The drug itself hasn’t been thoroughly tested on humans in an official capacity. Nonetheless, it’s been a fan-favorite among bodybuilders for over thirty years now since it has a great effect on the body’s metabolism. Keep in mind Cardarine is banned by the world anti-doping agency.


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