Ibutamoren: What it is and how it works
Ibutamoren, formerly known as Nutrobal or MK-677, is a new drug in the world of bodybuilding. Its benefits have not been officially confirmed yet, but more than a few people swear by it. Even though it’s mainly associated with bodybuilders, people with disabilities and hormone deficiencies benefit from it as well.
Many people often mistake Ibutamoren for a steroid, which it is not. It is not a typical growth stimulator either.
Ibutamoren is a secretagogue that mimics ghrelin, a growth stimulator. It increases levels of the growth hormone in the plasma. However, it does not affect cortisol levels, which is great. Drugs that increase cortisol levels are usually very effective and fast, but they usually have terrible side-effects. Ibutamoren is not like that, its effects are positive and most long-lasting.
Originally named Nutrobal, Ibutamoren first started as a hormone booster that was used to help people with insulin and growth hormone deficiencies. The first brand that started producing it is Oratrope. Back then, its status was ‘experimental’. It quickly gained popularity because of bodybuilders who started using it to gain mass. Basically, Ibutamoren enabled them to quickly gain muscle and get rid of fat. So it’s no wonder that it blew up so quickly.
Today, Ibutamoren is still not approved by the FDA. It’s currently in the preclinical phase, and it is yet to be clinically tested. However, that doesn’t stop people from trying it out. Many people claim that Ibutamoren changed their life, and some even call it an ‘elixir of youth’. Even if that is true, we suggest you don’t try it on your own. If you want to try it, consult with your doctor first.
- Anti-aging abilities
- Increases cognitive funtions
- Cardiovascular benefits
- Increases tissue recovery
- Improves sleep
- No negative side effects
Medical Uses of Ibutamoren
As we’ve said in the previous paragraph, Ibutamoren has many uses. Whether it’s to help recover from an illness or just to gain muscle, many people opt for this supplement as treatment.
1. Bodybuilding and Muscle Gain
Ibutamoren stimulates the IGFs (insulin-like growth factors), and thus increases the lean body mass without affecting the fat mass too.
In other words, taking Ibutamoren will help your muscles grow faster. Your appetite will increase too, but the calories you intake will be distributed differently. Besides, if you exercise regularly, you can get bulky pretty fast.
2. Increasing Bone Density
Bone density diminishes with age. A big number of elderly people suffer from osteoporosis and bone frailty, which causes severe pain and general lack of mobility. Some young adults and children experience this as well, but it is usually due to an illness.
Ibutamoren activates the growth hormone, which then stimulates bone turnover. That’s why it can actually help strengthen bones.
3. Helping with Growth Hormone Deficiency
Some children and adults suffer from growth hormone deficiency. And since Ibutamoren increases the IGF-1 hormone, it can help said people make up for the deficiency.
The great thing about this supplement is that it’s safe for both children and adults. It doesn’t increase the cortisol, thyrotropin, glucose, or prolactin levels.
However, we still have to keep in mind that Ibutamoren has not been approved yet. Using it as treatment is still not a common practice. Some patients have had major success using it, but on the other hand, some haven’t.
4. Weight Loss/Gain
Ibutamoren boosts the appetite, and thus also increases the calorie intake. This may seem counterproductive, but it’s actually not. Most of the calories go to the muscles, so your body is basically forced to use the fat reserves to metabolize. In other words, Ibutamoren redirects calories to the muscles and burns the fat instead.
5. Improving Sleep Quality and Cognitive Functions
When it comes to sleep, Ibutamoren has shown some positive effects. Users who took Ibutamoren for various reasons have reported that it has improved their quality of sleep as well. It increased the duration of REM, which is the stage that involves deep sleep and thought processing.
And without sleep, our cognitive functions would be lacking big time. During sleep, our body naturally secretes the growth hormone. Thanks to this hormone, our memory and learning abilities can recover while we sleep. Because Ibutamoren artificially stimulates the growth hormone, it can have similar effects on our body.
6. Rejuvenating the Muscles
Some people say that Ibutamoren is an ‘elixir of youth’ and that it has rejuvenating powers. There’s actually a very simple and valid explanation for this. As we already know, Ibutamoren helps build lean body mass and bone density. With age, the muscles start deteriorating, and it’s much harder to build them again. That’s why elderly people, or people who suffered from serious injuries, take Ibutamoren to gain strength.
First of all, Ibutamoren improves lean body mass. In the Rochester University study, a group of overall healthy 60-year-olds took Ibutamoren supplements for three months. Most of them had shown a significant increase in lean body mass.
Another study, in Seoul, tested the properties of Ibutamoren. This time, the subjects were women aged 22–46 years old, and this time, they were following a diet prescribed by the researchers. These subjects also showed major improvement in lean body mass. In addition, they also experienced a major fat loss.
Believe it or not, Ibutamoren was also proven to successfully treat growth hormone deficiency in both adults and children. One Chilean study treated 18 prepubescent children who suffered from this deficiency with MK-677. The results were surprisingly positive — the supplement was able to make up for the deficiency. And not just that, it was able to do so without affecting the cortisol, insulin, thyroxine, thyrotropin, or prolactin levels. A similar study was later conducted on adult men, and its results were similar. MK-677 treated their deficiency. However, this time, it did affect their insulin and glucose levels.
When it comes to bone density and bone turnover, Ibutamoren has also shown success. There were more than a few studies on this topic. One tested obese men, while others tested menopausal women and elders. But all of them proved that Ibutamoren accelerates bone turnover and increases bone density. Bone density improvement shows up in about a year or so, whereas bone turnover acts faster than that.
Ibutamoren also has anti-aging properties and slows down muscle wasting. An interesting study in Israel backs this up. The research included elderly patients with hip fractures. After a few months, the subjects that took Ibutamoren daily were more successful at stair climbing and had fewer falls than those who took the placebo. They quickly regained their speed of motion. Basically, Ibutamoren can help patients recover faster from their injuries and get their strength back.
Sleep and cognitive function can also improve, thanks to Ibutamoren. Not only does it prevent cognitive decline that comes naturally with old age but also enhances memory capacity. It can basically slow down the progression of Alzheimer’s. Scientists say that this may be because of MK-677’s positive effects on sleep. In case you don’t remember, Ibutamoren also prolongs the REM stage of sleep.
Oddly enough, Ibutamoren can also help regenerate tissue faster. One Texas study tested Ibutamoren on children who had severe burn injuries. The patients who took MK-677 took much less time to heal than those who didn’t. Scientists say that the reason behind this is the Ibutamoren’s effect on the growth hormone.
Oddly enough, some Ibutamoren users even claim that it helps alleviate hangovers. This claim wasn’t backed up by any research, but it’s still an interesting one.
We’ve done nothing but praise Ibutamoren so far. Now it’s time to address its potential side-effects. They are actually quite minimal, but they’re important to know as well.
- The first side-effect is the increase in appetite. Although some users (bodybuilders, for instance) might find this normal, even beneficial, some might not.
- Some users reported mild swelling and muscle pain. The reasons for this are still unknown.
- A few Ibutamoren users also experienced abnormally high blood pressure and glucose levels, as well as insulin resistance.
Although all of these side-effects are rare and/or minimal, we still advise you to consult a specialist before taking this supplement.
Because of its potential side-effects, those who have diabetes, heart diseases, or TH1 immune response should avoid Ibutamoren altogether.
The overall safest dosage of Ibutamoren you can take is 25mg, once a day. Anything over that might be dangerous for you, so please keep that in mind before you take anything. The average dosage cycle is about 8 weeks, and it’s typically taken orally.
There was one study that showed effects of different dosage levels of Ibutamoren. Subjects who took 50mg a day showed a major increase in the IGF-1 concentration than those who took 10mg. However, those who took the lower dosage had the same growth hormone levels.
The takeaway from this study is that the dosage of MK-677 has to be adjusted for your particular needs and goals. For example, if you want to lose weight, it’s better to go with the 10mg dose. But if you want to gain muscle, then the 50mg dose is for you.
Stacking Ibutamoren with Other SARMs
Like we’ve said before, Ibutamoren has minor side-effects, but it should still not be taken lightly. You still have to be careful when choosing your dose, especially if you plan on stacking it with other SARMs. And then you also have to figure out how to stack them.
But if you do choose the right dose and stack your SARMs properly, then you can expect amazing results in a short amount of time. Ibutamoren can actually enhance the effects of the SARMs that you’re currently taking.
MK-677 works best when stacked with Cardarine, Ligandrol, and Testolone.
Stacking with Cardarine
Cardarine (or GW, or Endurobol) has not been clinically tested or approved yet either, but much like our beloved Ibutamoren, it’s said to work wonders. The most prominent effect of Cardarine is increasing endurance. That’s why many athletes use it regularly.
MK-677 and Cardarine is basically a dream combination. MK-677 will make you gain massive muscles, while the Cardarine will help you get there a lot faster. The preferred dose is 10mg of Cardarine and 25mg of Ibutamoren a day.
Stacking with Ligandrol
Much like Ibutamoren, Ligandrol increases lean body mass and decreases body fat. Stacked together, these two SARMs are very powerful. They are especially effective for bulking.
The safe and recommended dosage for men is 10mg per day, 8 to 12 weeks. Stack that with 25mg of MK-667, and you’re good to go.
Stacking with Testolone
Testolone, more famously known as RAD-140, is yet another SARM that increases the size of your muscles and helps you lose unnecessary weight. This supplement has a very similar effect to anabolic steroids, but it doesn’t have the horrible side-effects.
MK-677 mixed with Testolone gives fast and effective results. Obese and overweight people benefit from this combo the most since it enables them to lose half of their weight in no time.
The recommended dosage for RAD-140 is 20–30mg a day, for not more than 12 weeks.
Some users even report that the best stacking combination ever is MK-677 with RAD-140 and Ligandrol. Imagine the results you could get with that!
What to Expect Regarding Muscle Size Gain
It’s safe to say that Ibutamoren has many benefits, one of which is muscle growth. Although it may not be as powerful as the Testolone, for example, it’s still better than nothing. Plus, it has other benefits that you can look forward to, such as better sleep quality.
Provided that you take the right dose of MK-677 and work out regularly, you should see results in about a month. Your appetite will increase very quickly, whereas the fat loss will start in a couple of weeks. But after a month, you’ll be able to notice significant muscle growth.
Ibutamoren is one of the most praised SARMs out there, and for a good reason. It has plenty of benefits, yet very little side-effects. Besides that, many use it to treat illnesses and deficiencies.
The best way to use this supplement is by stacking it with other SARMs that are compatible with it. After doing so, you’ll surely be able to reach your fitness goals!
However, we urge you to be careful with supplements. Always do research and consult a specialist before taking anything.