LGD 3303, the new kid on the block
Ever since SARMs have appeared on the market, the hype hasn’t subsided. There are some that are already famous for their exceptional results, and some that are just now entering the market. LGD 3303 is relatively new, so don’t try it out until you have read this review! Selective androgen receptor modulators are a new class of synthetic drugs that deliver results very similar to those of anabolic steroids. However, just like anabolics, these drugs can have some serious side effects.
When I first heard about them, I had to do some serious research. Although these supplements are incredibly popular, the amount of info about them isn’t exactly what you would call abundant.
So if you’ve tried to find some useful info about LGD 3303 and have only found super-positive reviews, you ran into sponsored blog posts.
That’s why I did in-depth research regarding LGD 3303. Here, you can learn how it works, what it is used for, how quick it is and how effective, as well as which SARMS you can stack it with, its benefits, dosages, and side effects.
What Is LGD 3303?
According to its users, LGD 3303 is one of the best SARMS for overall strength and mass gains. This selective androgen receptor modulator comes with flawless oral bioavailability. Once ingested, this SARM binds to the androgen receptor with high affinity and selectivity. As a result, it causes a significant increase in muscle strength and size.
Basically, it allows users to utilize this SARM to the maximum with simple oral supplementation. Yup, I like that as well — in fact, it means that you won’t have to have anything to do with needles.
LGD 3303 is officially categorized as a selective agonist for the androgen receptor. Regarding how androgenic it is, it is a full agonist on muscle and a partial agonist on the prostate. It delivers both androgenic and anabolic effects and is currently a part of an osteoporosis treatment study.
The History of LGD 3033
Before I even consider using something, I need to know what it was made for. However, since SARMs are all relatively new, most manufacturers make them with an idea in mind and then test to see how well their intentions were translated into reality. But that doesn’t mean that they are just throwing chemicals in a tub and waiting to see what happens. However, it does mean that they have to go through lengthy trial phases before they can claim with certainty that their products do one thing or the other.
Ligand Pharmaceuticals is the company that makes this particular SARM. Furthermore, they are in the business of discovering and developing new drugs based on gene transcription technology, primarily intracellular receptors. The idea behind this SARM was making an oral supplement that can have a positive effect on bone and muscle mass.
In fact, Ligand Pharmaceuticals Incorporated started preclinical studies on SARM LGD 3303 in 2007, at the American Society for Bone and Mineral Research Annual Meeting. Furthermore, according to rat model data from that research, it shows the potential to increase muscle mass and BMD. And according to research done in previous years, LGD 3303 doesn’t negatively impact androgenic organs.
However, like many SARMs, this one is also brand new, and it still isn’t officially released for human consumption.
According to research, LGD 3303 can have various medical applications. SARMs are a bit more complicated than your standard Aspirin. Because they are selective androgen receptor modulators, they can also have some unexpected effects. That is why LGD 3303 is a part of numerous clinical trials.
Firstly, it can stimulate aspects of female sexual behavior and can potentially serve as a potential therapy for women with sexual desire disorders. In fact, according to research conducted in 2010 at the University of Arizona College of Medicine, this selective androgen receptor enhances male-directed sexual preference in female rats.
At the moment, this SARM is being tested for its potential as an osteoporosis treatment. Since osteoporosis leads to bone weakness and increased danger of bones breaking, it makes sense that a SARM like this can have the potential to relieve symptoms.
Moreover, according to recent animal studies, LGD 3303 enhances the effectiveness of bisphosphonate drugs. These drugs prevent the loss of bone density and are used to treat osteoporosis and similar conditions.
Also, it has the potential to maintain lean tissues and muscles among the aged, which can prevent numerous medical problems and raise their life quality.
Although human trials have not yet begun, the medical community considers that this drug can help in the treatment of some serious conditions.
What Is It Usually Used For?
In the world of professional sport, LGD 3303 is used to allow athletes significant muscle mass gains and to boost their muscle activity.
However powerful, most supplements have a singular use — they can be great for bulking, cutting, or recomping. But LGD 3303 is great for each of these purposes and will show amazing results.
Although an athlete might fail a drug test because of using LGD 3303, it is unlikely. This SARM is still rather new, so the World Anti-Doping Agency still hasn’t developed a test for it.
It offers results similar to anabolic steroids such as Dianabol, Sustanon, Trenbolone, and Deca Durabolin. But it offers those results without the dreadful side effects that potentially come with each of these anabolics.
Here’s what matters the most. You see, many supplements have very vague explanations regarding how exactly they work and what their effect on your organism is. In fact, those explanations are my main way of differentiating snake oil peddlers from legit supplement manufacturers.
Well, you’ll be glad to hear that this one is legit.
Once you take LGD 3303 orally or inject it, it will trigger androgenic action on a cellular level. Furthermore, it won’t simply trigger androgenic effects in every cell of your body. No. This SARM is selective, and instead of triggering every cell, it will only do so for skeletal and muscle tissue cells.
As a result, this compound helps increase muscle mass easily while at the same time improving bone density and strengthening bones.
What Can I Expect from LGD 3303?
LGD 3303 is among the most potent SARMs when it comes to strength and size gains.
In the bodybuilding community, this supplement is known for providing significant muscular fullness in spite of the fact that it is a dry compound. On the one hand, this might be a result of increased nitrogen retention, but on the other, it could be because of its nutrient partitioning effects. Either way, you will get muscles that “pop”, which is an effect you usually can get with dry compounds.
The visible results are rather fast with this SARM — a boost in size is visible within days, while dry mass gains become apparent in a matter of weeks. Even better, since these are dry mass gains, there’s no blurring of muscle definition whatsoever.
You can expect longer, more intense workout sessions with LGD 3303, followed by an amazing increase in strength and size.
Although the very first results will be visible within days, it’s best to wait until the full cycle is done to measure the impact of this SARM.
Benefits of LGD 3303
Unlike many other SARMs, this one has very few side effects, but many advantages:
Increases muscle activity, bone density, and muscle mass. This feature is immensely important for bodybuilders. Although most SARMs will increase muscle building, this one will strengthen the bones. Whether you’re bulking or cutting, you need your bones to be able to withstand the pressure. LDG 3303 makes it possible.
Offers effective androgenic action without affecting androgenic organs. This is a big advantage, especially when you compare LGD 3303 with steroids that have numerous dangerous side effects.
Speeds up the metabolism. Improving metabolic action is a big deal. If you want to cut fat, you can use this SARM to make it easier. However, if you want to get the most out of your cutting cycle, you will need to stack LGD 3303 and have a strong exercise regimen.
It can be stacked with other SARMs. This is a relevant benefit because if you want to speed up your bulking results, you will want to use several supplements at once for the best effect.
Comes with no virilization risks, which means that women can use it safely. Although this may be the case, it is still recommended for women to get a physician’s advice before starting an LGD 3303 cycle.
- Doesn’t affect the size of the prostate gland
- Doesn’t affect the natural testosterone production
- Improves the anabolic effect of androgens in bone and muscle tissues
- Has minimal negative effects
LGD 3303 Side Effects
However, although side effects aren’t numerous, they still do exist. You see, even if you like every benefit a SARM can offer, you still need to be well aware of potential dangers that come with its use as well.
Since LGD 3303 is still in the trial phase, I can’t really say if there are any more side effects or not. I can only present to you what research done so far has shown and what users mentioned.
Here are the potential side effects of LGD 3303:
Testosterone suppression symptoms. Since this SARM is very suppressive, if you’re prone to these symptoms, they may appear during the cycle. Symptoms may include breast tissue swelling, increased fatigue, hot flashes, body hair decrease, low sex drive, and mood changes. If you notice any of these symptoms during your LGD 3303 cycle, you will need a full PCT post cycle.
Estrogen level increase. This could lead to gynecomastia and other estrogen related symptoms during the cycle. An aromatase inhibitor, such as Arimistane, can help prevent this if you use it during the LGD 3303 cycle.
LGD 3303 has a relatively short half-life of about 6 hours. That means that dosing should be more frequent so that you can maintain a stable concentration of this SARM in your blood throughout the day. Users claim that three to four doses per day are the best for LGD 3303.
Dosages of LGD 3303 depend on the purpose you have in mind. Also, since the research on this drug is still in progress, you might need to fine-tune the dosage that suits you.
However, according to users, you can expect significant results at doses of 10mg or higher, while the sweet spot lies near the 20mg range.
If you’re cutting, it’s recommended to use 15–20mg per day during the entire 6– 8-week cycle.
On the other hand, if you’re bulking and you want optimal results, you should use between 20–30mg per day, during an 8– 10-week cycle.
And lastly, if you’re recomposing, the bulking dosages will be best for achieving desired results.
Will I Need PCT After LGD 3303
According to research, LGD 3303 has flawless androgenic effects. However, it doesn’t affect the androgenic organs. Basically, this means that this SARM doesn’t affect the natural testosterone production in the body. As a result, there’s no need for a post cycle therapy.
After this supplement, you can continue your activities normally, without the need to stabilize your hormones, as you would after an anabolic cycle.
Stacking with Other SARMS
For the fastest results, you can stack LGD 3303 with GW 501516. Also known as Cardarine, this one destroys unwanted body fat, increases endurance, and reduces recovery time.
You can also stack it with its younger brother, LGD 4033. Also known as Ligandrol, this SARM boosts strength levels, improves lean muscle mass, and has muscle healing properties.
What Do the Users Say?
As with every supplement, effects depend on the dosage, diet, and exercise. So I had to hit the forums and see how people used this SARM if they stacked it or not, and how big their doses were.
Since it’s new, most people don’t want to do full doses in their first cycle, so they’re testing it.
For instance, one reviewer claims to have used 5mg per day for 8 weeks. He’s satisfied with the results, claims to have added 55 pounds to his bench, and that LGD 3303 had a good recomp effect.
Another user claims to have gained 14 pounds during an 8-week cycle, with a dose of 10mg per day.
However, all of them agree that their gains were already visible after the first three or four days, that their muscles felt harder, their endurance went up, and that they didn’t experience any side effects whatsoever.
In the End
LGD 3303 is another amazing SARM to consider if you don’t want to go full natty, don’t want to use androgenic steroids, and you don’t want to take the slow, natural supplement route.
Although it is still rather new, I can clearly see that it has a ton of potential.